1. The Technician 2. The time of procedure 3. Hormones of the individual The Technician should be certified on the specific Laser that is being used and familiar with the setting that will be the best and most effective on various patients. For Example: Someone with darker skin and course hair will have a setting different than someone with light skin and softer hair. If the wrong settings are used this could result in Hyperpigmentation of the skin or ineffective treatments. Don’t waste your money!